United States of America Remote (Global)

Illumina, Inc. is hiring a Sr Bioinformatics Scientist

About the Role

As a Senior Bioinformatics Scientist, you will drive the creation and refinement of secondary analysis algorithms focused on detecting genetic variants and biomarkers in cancer through next-generation sequencing. Your work will directly inform the evolution of clinical genomics tools, with a focus on improving accuracy, scalability, and clinical applicability.

Key Responsibilities

  • Evaluate and enhance current bioinformatics pipelines for variant and biomarker identification
  • Design and implement prototype algorithms to advance analytical capabilities
  • Collaborate with internal and external research teams to plan and interpret experiments supporting oncology assay development
  • Offer technical expertise to cross-functional groups, including engineering, clinical, and research partners
  • Contribute independently to R&D initiatives integrating assays and computational methods
  • Communicate technical strategies and findings clearly across disciplines

Qualifications

Candidates must have at least five years of relevant experience with a Bachelor’s degree, three years with a Master’s, or a PhD without minimum experience. Equivalent professional experience is acceptable. Fluency in at least two of the following is required: statistical analysis, standard bioinformatics techniques, NGS data interpretation, or oncology. You should have hands-on experience building custom bioinformatics algorithms, not just applying existing tools.

Proficiency in programming languages such as Python is essential. Strong interpersonal and communication skills are necessary for effective collaboration in multidisciplinary environments.

Preferred Background

  • PhD in bioinformatics, computational biology, statistics, mathematics, or a related discipline
  • Experience working with C++

Technology Environment

The role leverages Python and C++ within the context of NGS data analysis, focusing on variant calling, biomarker detection, and algorithm development for the DRAGEN platform. You will work in a high-performance computing environment designed for clinical genomics applications.

Work Environment

This position is available remotely within the United States, with the expectation that your schedule accommodates overlap with Pacific time zone working hours. The role supports a globally distributed team and emphasizes flexible, inclusive collaboration.

Company Values

The organization fosters a culture rooted in innovation, openness, and inclusion. It actively promotes belonging, diversity, and empowerment, seeking diverse perspectives to advance scientific discovery. A zero-net pay gap policy ensures equitable compensation across gender, ethnicity, and race. Employee Resource Groups support career growth, cultural fluency, and community engagement.

Benefits

  • Health, dental, and vision coverage
  • Retirement planning support
  • Paid time off and family planning resources
  • Variable cash incentives, including bonus or commission programs
  • Equity eligibility for eligible positions
  • Access to genomic sequencing technology

Compensation

The base salary range for this role is $129,400 to $194,000. Additional compensation may include equity and participation in variable cash programs. All employees are eligible for incentive programs based on performance.

Equal Opportunity Employer

The company is committed to equal employment opportunity regardless of sex, race, religion, color, gender identity, sexual orientation, pregnancy, ancestry, national origin, age, disability, medical condition, marital or domestic partner status, military or veteran status, citizenship, or genetic information. Background checks are conducted in compliance with applicable laws, and individuals with arrest or conviction records will be considered in accordance with local, state, and federal regulations.

Required Skills
PythonC++StatisticsBioinformaticsNGS AnalysisOncologyAlgorithm DevelopmentCommunicationCross-functional Collaboration PythonC++next-generation sequencing (NGS)DRAGENvariant callingbiomarker detectionalgorithm developmentbioinformaticsNGS analysisoncologystatisticsprogrammingcommunication skills
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About company
Illumina, Inc.
At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients.
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Posted a month ago